
Affect of swimming train on the expression
Seth
- 0
Have an effect on of swimming prepare on the expression of apoptotic gene caspase-Three in chondrocytes in osteoarthritis
Objective: To assessment swimming prepare’s influence on caspase-3 expression in chondrocytes in osteoarthritis (OA).
Methods: 36 SD rats had been randomly separated into common group (n = 12), OA model group (n = 12) and swimming prepare group (n = 12). After modeling, rats obtained no intervention in model group and swimming prepare as quickly as a day (15 min/time) for 4 consecutive weeks in swimming prepare group. After intervention for 4 weeks, specimens had been taken to analysis tissue morphology by H&E staining, caspase-Three expression by Western blot and qPCR, chondrocytes apoptosis by TUNEL assay.
Outcomes: HE staining revealed irregular bone tissue morphology in model group and swimming prepare group with improved morphology after swimming prepare. Model group and swimming prepare group all confirmed significantly bigger Caspase-Three protein diploma than common group with lower diploma after swimming prepare (P < 0.05). Persistently, qPCR confirmed comparable expression profile of caspase-Three mRNA diploma to the protein diploma.

anti-CD300 antigen |
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YF-PA17583 | Abfrontier | 50 ul | EUR 435.6 |
Description: Mouse polyclonal to CD300 antigen |
anti-CD300 antigen |
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YF-PA17584 | Abfrontier | 50 ug | EUR 435.6 |
Description: Mouse polyclonal to CD300 antigen |
anti-CD300 antigen |
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YF-PA17585 | Abfrontier | 50 ul | EUR 435.6 |
Description: Mouse polyclonal to CD300 antigen |
Mouse Anti Melanoma associated antigen ELISA kit |
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E03M0220-192T | BlueGene | 192 tests | EUR 1524 |
Description: A competitive ELISA for quantitative measurement of Mouse Anti Melanoma associated antigen in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species. |
Mouse Anti Melanoma associated antigen ELISA kit |
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E03M0220-48 | BlueGene | 1 plate of 48 wells | EUR 624 |
Description: A competitive ELISA for quantitative measurement of Mouse Anti Melanoma associated antigen in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species. |
Mouse Anti Melanoma associated antigen ELISA kit |
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E03M0220-96 | BlueGene | 1 plate of 96 wells | EUR 822 |
Description: A competitive ELISA for quantitative measurement of Mouse Anti Melanoma associated antigen in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species. |
Mouse Anti soluble liver antigen ELISA kit |
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E03S0263-192T | BlueGene | 192 tests | EUR 1524 |
Description: A competitive ELISA for quantitative measurement of Mouse Anti soluble liver antigen in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species. |
Mouse Anti soluble liver antigen ELISA kit |
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E03S0263-48 | BlueGene | 1 plate of 48 wells | EUR 624 |
Description: A competitive ELISA for quantitative measurement of Mouse Anti soluble liver antigen in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species. |
Mouse Anti soluble liver antigen ELISA kit |
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E03S0263-96 | BlueGene | 1 plate of 96 wells | EUR 822 |
Description: A competitive ELISA for quantitative measurement of Mouse Anti soluble liver antigen in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species. |
Mouse Anti-EBV Nuclear Antigen Monoclonal Antibody |
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DMAB3332-05mg | Creative Diagnostics | 0.5 mg | EUR 1162.8 |
Mouse Anti-EBV Nuclear Antigen Monoclonal Antibody |
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DMAB3332-1mg | Creative Diagnostics | 1 mg | EUR 1762.8 |
Anti-Ku80 Antigen Purified |
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11-496-C025 | ExBio | 0.025 mg | EUR 129.6 |
Anti-Ku80 Antigen Purified |
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11-496-C100 | ExBio | 0.1 mg | EUR 212.4 |
Anti-Carcinoembryonic Antigen antibody |
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STJ16100878 | St John's Laboratory | 1 mL | EUR 801.6 |
Anti-Nucleolar Antigen antibody |
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STJ16101002 | St John's Laboratory | 100 µg | EUR 424.8 |
Anti-Liver Antigen antibody |
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STJ16101073 | St John's Laboratory | 100 µg | EUR 424.8 |
Anti-Liver Antigen antibody |
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STJ16101074 | St John's Laboratory | 100 µg | EUR 424.8 |
Anti-Carcinoembryonic Antigen antibody |
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STJ96963 | St John's Laboratory | 200 µl | EUR 236.4 |
Description: Carcinoembryonic antigen is a protein encoded by the CEACAM5 gene which is approximately 76,7 kDa. Carcinoembryonic antigen is localised to the cell membrane. It is involved in the metabolism of proteins and hematopoietic stem cell differentiation pathways and lineage-specific markers. It is a cell surface glycoprotein that plays a role in cell adhesion and in intracellular signalling. It may also regulate differentiation, apoptosis, and cell polarity and is used as a clinical biomarker for gastrointestinal cancers. Carcinoembryonic antigen is expressed in the intestine, liver, saliva, stomach and lung. Mutations in the CEACAM5 gene may be involved in urachal cancer. STJ96963 was developed from clone 10E1 and was affinity-purified from mouse ascites by affinity-chromatography using specific immunogen. This primary antibody detects endogenous Carcinoembryonic antigen proteins. |
anti-Prostate Specific Antigen |
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YF-PA10281 | Abfrontier | 50 ug | EUR 435.6 |
Description: Mouse polyclonal to Prostate Specific Antigen |
anti-Prostate Specific Antigen |
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YF-PA10282 | Abfrontier | 100 ug | EUR 483.6 |
Description: Rabbit polyclonal to Prostate Specific Antigen |
Mouse IgG Antigen |
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IM122 | Cygnus Technologies | 1 ml | EUR 342 |
Description: Mouse IgG Antigen by Cygnus Technologies is available in Europe via Gentaur. |
Rat Anti Mouse F4/80 Antigen Monoclonal Antibody |
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CABT-47632RM | Creative Diagnostics | 0.1 mg | EUR 795.6 |
Mouse Anti-Bacillus anthracis Protective Antigen Monoclonal Antibody |
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DMAB3024 | Creative Diagnostics | 1 mg | EUR 1083.6 |
Mouse Anti-Bacillus anthracis Protective Antigen Monoclonal Antibody |
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DMAB3028 | Creative Diagnostics | 1 mg | EUR 1146 |
Mouse Anti-Bacillus anthracis Protective Antigen Monoclonal Antibody |
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DMAB3029 | Creative Diagnostics | 1 mg | EUR 1146 |
Mouse Anti-Bacillus anthracis Protective Antigen Monoclonal Antibody |
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DMAB3031 | Creative Diagnostics | 1 mg | EUR 1083.6 |
Mouse Anti-Bacillus anthracis Spore Antigen Monoclonal Antibody |
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DMAB3033-05mg | Creative Diagnostics | 0.5 mg | EUR 1162.8 |
Mouse Anti-Bacillus anthracis Spore Antigen Monoclonal Antibody |
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DMAB3033-1mg | Creative Diagnostics | 1 mg | EUR 1762.8 |
Mouse Anti-Bacillus anthracis Spore Antigen Monoclonal Antibody |
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DMAB3034-05mg | Creative Diagnostics | 0.5 mg | EUR 1162.8 |
Mouse Anti-Bacillus anthracis Spore Antigen Monoclonal Antibody |
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DMAB3034-1mg | Creative Diagnostics | 1 mg | EUR 1762.8 |
Mouse Anti-Hepatitis B Core Antigen Monoclonal Antibody |
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DMAB3498 | Creative Diagnostics | 1 mg | EUR 999.6 |
Mouse Anti-Hepatitis B Surface Antigen Monoclonal Antibody |
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DMAB3525 | Creative Diagnostics | 1 mg | EUR 937.2 |
Mouse Anti-Hepatitis B Surface Antigen Monoclonal Antibody |
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DMAB3531 | Creative Diagnostics | 1 mg | EUR 889.2 |
Mouse Anti-Hepatitis B Surface Antigen Monoclonal Antibody |
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DMAB3532 | Creative Diagnostics | 1 mg | EUR 889.2 |
Mouse Anti-Hepatitis B Surface Antigen Monoclonal Antibody |
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DMAB3536-05mg | Creative Diagnostics | 0.5 mg | EUR 1162.8 |
Mouse Anti-Hepatitis B Surface Antigen Monoclonal Antibody |
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DMAB3536-1mg | Creative Diagnostics | 1 mg | EUR 1762.8 |
Mouse Anti-Hepatitis B Surface Antigen Monoclonal Antibody |
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DMAB3537-05mg | Creative Diagnostics | 0.5 mg | EUR 1162.8 |
Mouse Anti-Hepatitis B Surface Antigen Monoclonal Antibody |
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DMAB3537-1mg | Creative Diagnostics | 1 mg | EUR 1762.8 |
Mouse Anti-Hepatitis B Surface Antigen Monoclonal Antibody |
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DMAB3540 | Creative Diagnostics | 1 mg | EUR 889.2 |
Mouse Anti-Hepatitis B Surface Antigen Monoclonal Antibody |
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DMAB3543 | Creative Diagnostics | 1 mg | EUR 889.2 |
Mouse Anti-Hepatitis B Surface Antigen Monoclonal Antibody |
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DMAB3545 | Creative Diagnostics | 1 mg | EUR 758.4 |
Mouse Anti-Hepatitis B Surface Antigen Monoclonal Antibody |
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DMAB3546 | Creative Diagnostics | 1 mg | EUR 758.4 |
Mouse Anti Borrelia Burgdorferi Flagellar Antigen Monoclonal Antibody |
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DMABT-51105MB | Creative Diagnostics | 0.2 mg | EUR 858 |
Mouse Anti Chlamydia Trachomatis 30Kda Antigen Monoclonal Antibody |
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DMABT-51152MC | Creative Diagnostics | 0.2 mg | EUR 795.6 |
Mouse Anti Hepatitis A Surface Antigen Monoclonal Antibody |
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DMABT-51310MH | Creative Diagnostics | 0.2 mg | EUR 889.2 |
Mouse Anti Hepatitis B Core Antigen Monoclonal Antibody |
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DMABT-51311MH | Creative Diagnostics | 0.2 mg | EUR 920.4 |
Mouse Anti Hepatitis B Core Antigen Monoclonal Antibody |
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DMABT-51312MH | Creative Diagnostics | 0.2 mg | EUR 852 |
Mouse Anti Hepatitis B Core Antigen Monoclonal Antibody |
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DMABT-51314MH | Creative Diagnostics | 0.2 mg | EUR 696 |
Mouse Anti Hepatitis B Core Antigen Monoclonal Antibody |
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DMABT-51315MH | Creative Diagnostics | 0.2 mg | EUR 852 |
Mouse Anti Hepatitis B Core Antigen Monoclonal Antibody |
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DMABT-51316MH | Creative Diagnostics | 0.2 mg | EUR 795.6 |
Mouse Anti Hepatitis B Core Antigen Monoclonal Antibody |
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DMABT-51317MH | Creative Diagnostics | 0.2 mg | EUR 852 |
Mouse Anti Hepatitis B E Antigen Monoclonal Antibody |
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DMABT-51319MH | Creative Diagnostics | 0.2 mg | EUR 920.4 |
Mouse Anti Hepatitis B Surface Antigen Monoclonal Antibody |
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DMABT-51323MH | Creative Diagnostics | 0.2 mg | EUR 696 |
Mouse Anti Hepatitis B Surface Antigen Monoclonal Antibody |
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DMABT-51324MH | Creative Diagnostics | 0.1 ml | EUR 534 |
Mouse Anti Hepatitis B Surface Antigen Monoclonal Antibody |
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DMABT-51325MH | Creative Diagnostics | 1 ml | EUR 982.8 |
Mouse Anti Hepatitis B Surface Antigen Monoclonal Antibody |
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DMABT-51326MH | Creative Diagnostics | 1 ml | EUR 534 |
Mouse Anti Hepatitis B Surface Antigen Monoclonal Antibody |
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DMABT-51327MH | Creative Diagnostics | 6 ml | EUR 858 |
Mouse Anti Hepatitis B Surface Antigen Monoclonal Antibody |
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DMABT-51328MH | Creative Diagnostics | 0.1 mg | EUR 889.2 |
Mouse Anti Hepatitis B X Antigen Monoclonal Antibody |
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DMABT-51330MH | Creative Diagnostics | 0.25 mg | EUR 870 |
Mouse Anti Hepatitis C Core Antigen Monoclonal Antibody |
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DMABT-51332MH | Creative Diagnostics | 0.1 mg | EUR 920.4 |
Mouse Anti Hepatitis C E1 Antigen Monoclonal Antibody |
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DMABT-51333MH | Creative Diagnostics | 0.1 mg | EUR 1132.8 |
Mouse Anti Hepatitis C E2 Antigen Monoclonal Antibody |
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DMABT-51334MH | Creative Diagnostics | 0.1 mg | EUR 1132.8 |
Mouse Anti Influenza A H5 Antigen Monoclonal Antibody |
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DMABT-51386MI | Creative Diagnostics | 0.2 mg | EUR 795.6 |
Mouse Anti Influenza A H5 Antigen Monoclonal Antibody |
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DMABT-51388MI | Creative Diagnostics | 0.2 mg | EUR 889.2 |
Mouse Anti Mycobacterium Tuberculosis 16Kda Antigen Monoclonal Antibody |
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DMABT-51441MM | Creative Diagnostics | 0.1 mg | EUR 1070.4 |
Mouse Anti Mycobacterium Tuberculosis 16Kda Antigen Monoclonal Antibody |
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DMABT-51442MM | Creative Diagnostics | 0.1 mg | EUR 1070.4 |
Mouse Anti Mycobacterium Tuberculosis 38Kda Antigen Monoclonal Antibody |
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DMABT-51444MM | Creative Diagnostics | 0.2 mg | EUR 920.4 |
Mouse Anti Mycobacterium Tuberculosis 38Kda Antigen Monoclonal Antibody |
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DMABT-51446MM | Creative Diagnostics | 0.2 mg | EUR 920.4 |
Mouse Anti Mycobacterium Tuberculosis 38Kda Antigen Monoclonal Antibody |
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DMABT-51448MM | Creative Diagnostics | 0.2 mg | EUR 920.4 |
Mouse Anti Yersinia Pestis V Antigen Monoclonal Antibody |
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DMABT-51632MY | Creative Diagnostics | 0.2 mg | EUR 920.4 |
Mouse Anti Yersinia Pestis V Antigen Monoclonal Antibody |
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DMABT-51634MY | Creative Diagnostics | 0.2 mg | EUR 920.4 |
Mouse anti- extractable nuclear antigen antibody ELISA Kit |
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ELA-E1124m | Lifescience Market | 96 Tests | EUR 1038 |
anti-RhoD human antigen IgG1 |
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131-A-01mg | Virogen | 0,1 mg | EUR 321 |
Description: anti-RhoD human antigen IgG1 |
anti-RhoD human antigen IgG1 |
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131-A-1000ug | Virogen | 1000 ug | EUR 1539 |
Description: anti-RhoD human antigen IgG1 |
anti-Carcinoembryonic Antigen/CEA (10E1) |
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LF-MA20354 | Abfrontier | 100 ug | EUR 424.8 |
Description: Mouse monoclonal to Carcinoembryonic Antigen (CEA) |
Anti-HLA-DR antigen antibody |
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STJ16100045 | St John's Laboratory | 1 mL | EUR 573.6 |
Anti-CD95/FAS antigen antibody |
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STJ16100141 | St John's Laboratory | 100 µg | EUR 424.8 |
Anti-Rat CD4-antigen antibody |
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STJ16100150 | St John's Laboratory | 1 mL | EUR 724.8 |
Anti-Myeloid Specific Antigen antibody |
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STJ16100158 | St John's Laboratory | 100 µg | EUR 466.8 |
Anti-Myeloid Specific Antigen antibody |
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STJ16100170 | St John's Laboratory | 100 µg | EUR 466.8 |
Anti-Myeloid Specific Antigen antibody |
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STJ16100171 | St John's Laboratory | 100 µg | EUR 466.8 |
Anti-Myeloid Specific Antigen antibody |
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STJ16100172 | St John's Laboratory | 100 µg | EUR 466.8 |
Anti-Hepatocyte Specific Antigen antibody |
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STJ16100376 | St John's Laboratory | 1 mL | EUR 954 |
Anti-Melamona-Associated Antigen antibody |
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STJ16100389 | St John's Laboratory | 1 mL | EUR 1045.2 |
Anti-Melamona-Associated Antigen antibody |
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STJ16100390 | St John's Laboratory | 1 mL | EUR 1005.6 |
Anti-Melanoma Discr. Antigen antibody |
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STJ16100730 | St John's Laboratory | 1 mL | EUR 348 |
Anti-Melanoma Discr. Antigen antibody |
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STJ16100731 | St John's Laboratory | 1 mL | EUR 348 |
Anti-Melanoma Associated Antigen antibody |
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STJ16100732 | St John's Laboratory | 1 mL | EUR 303.6 |
Anti-Melanoma Associated Antigen antibody |
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STJ16100733 | St John's Laboratory | 1 mL | EUR 325.2 |
Anti-Melanoma Associated Antigen antibody |
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STJ16100734 | St John's Laboratory | 1 mL | EUR 325.2 |
Anti-Melanoma Associated Antigen antibody |
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STJ16100735 | St John's Laboratory | 1 mL | EUR 325.2 |
Anti-Ovarium Carcinoma Antigen antibody |
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STJ16100873 | St John's Laboratory | 1 mL | EUR 348 |
Anti-Leukocyte Common Antigen antibody |
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STJ16100941 | St John's Laboratory | 1 mL | EUR 577.2 |
Anti-Prostate Specific Antigen antibody |
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STJ16100961 | St John's Laboratory | 1 mL | EUR 577.2 |
Anti-Myeloid Specific Antigen antibody |
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STJ16100989 | St John's Laboratory | 100 µg | EUR 424.8 |
Anti-Anthrax Protective Antigen antibody |
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STJ99283 | St John's Laboratory | 200 µl | EUR 236.4 |
Description: Mouse monoclonal to Anthrax Protective Antigen. |
anti-NY-REN-50 antigen |
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YF-PA19832 | Abfrontier | 50 ul | EUR 435.6 |
Description: Mouse polyclonal to NY-REN-50 antigen |
anti-Blood Group Kell Antigen |
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YF-PA12828 | Abfrontier | 50 ul | EUR 435.6 |
Description: Mouse polyclonal to Blood Group Kell Antigen |
Anti-Prostate Specific Antigen (1B1) |
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YF-MA11962 | Abfrontier | 100 ug | EUR 435.6 |
Description: Mouse monoclonal to Prostate Specific Antigen |
Anti-Flavivirus group antigen Antibody |
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A1146-200 | Biovision | each | EUR 836.4 |
Anti-Flavivirus group antigen Antibody |
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A1147-200 | Biovision | each | EUR 836.4 |
Mouse CD63 antigen (Cd63) |
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1-CSB-EP004950MOe0 | Cusabio |
|
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Description: Recombinant Mouse CD63 antigen(Cd63) ,partial expressed in E.coli |
Mouse CD81 antigen (Cd81) |
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1-CSB-EP004960MO | Cusabio |
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Description: Recombinant Mouse CD81 antigen(Cd81),partial expressed in E.coli |
Mouse CD82 antigen (Cd82) |
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1-CSB-EP004961MO | Cusabio |
|
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Description: Recombinant Mouse CD82 antigen(Cd82) ,partial expressed in E.coli |
Rat Anti Mouse F4/80 Antigen Monoclonal Antibody,APC |
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CABT-47617RM | Creative Diagnostics | 100 TEST | EUR 920.4 |
Rat Anti Mouse F4/80 Antigen Monoclonal Antibody,Biotin |
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CABT-47620RM | Creative Diagnostics | 0.1 mg | EUR 889.2 |
Rat Anti Mouse F4/80 Antigen Monoclonal Antibody,FITC |
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CABT-47625RM | Creative Diagnostics | 0.1 mg | EUR 889.2 |
Mouse Monoclonal Anti-human carcinoembryonic antigen (CEA) (clone 1) |
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CEA11-M | Alpha Diagnostics | 500 ug | EUR 578.4 |
Mouse Monoclonal Anti-human carcinoembryonic antigen (CEA) (clone 2) |
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CEA12-M | Alpha Diagnostics | 500 ug | EUR 578.4 |
Mouse Anti paraneoplastic Ma antigen 2 antibody ELISA kit |
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E03A0480-192T | BlueGene | 192 tests | EUR 1524 |
Description: A competitive ELISA for quantitative measurement of Mouse Anti paraneoplastic Ma antigen 2 antibody in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species. |
Mouse Anti paraneoplastic Ma antigen 2 antibody ELISA kit |
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E03A0480-48 | BlueGene | 1 plate of 48 wells | EUR 624 |
Description: A competitive ELISA for quantitative measurement of Mouse Anti paraneoplastic Ma antigen 2 antibody in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species. |
Mouse Anti paraneoplastic Ma antigen 2 antibody ELISA kit |
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E03A0480-96 | BlueGene | 1 plate of 96 wells | EUR 822 |
Description: A competitive ELISA for quantitative measurement of Mouse Anti paraneoplastic Ma antigen 2 antibody in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species. |
Mouse Anti Epstein-Barr Virus Nuclear Antigen Monoclonal Antibody |
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DMABT-51237ME | Creative Diagnostics | 0.1 mg | EUR 982.8 |
Mouse Anti Epstein-Barr Virus Nuclear Antigen Monoclonal Antibody |
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DMABT-51238ME | Creative Diagnostics | 0.1 mg | EUR 858 |
Mouse Anti Hepatitis B Core Antigen Monoclonal Antibody,HRP |
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DMABT-51313MH | Creative Diagnostics | 0.1 mg | EUR 920.4 |
Mouse Anti Hepatitis C Ns-3 Antigen Monoclonal Antibody |
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DMABT-51336MH | Creative Diagnostics | 0.2 mg | EUR 920.4 |
Mouse Anti Hepatitis C Ns-3 Antigen Monoclonal Antibody |
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DMABT-51337MH | Creative Diagnostics | 0.2 mg | EUR 920.4 |
Mouse Anti Hepatitis C Ns-3 Antigen Monoclonal Antibody |
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DMABT-51338MH | Creative Diagnostics | 0.2 mg | EUR 920.4 |
Mouse Anti Hepatitis C Ns-3 Antigen Monoclonal Antibody |
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DMABT-51339MH | Creative Diagnostics | 0.1 mg | EUR 1132.8 |
Mouse Anti Hepatitis C Ns-3 Antigen Monoclonal Antibody |
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DMABT-51340MH | Creative Diagnostics | 0.1 mg | EUR 1132.8 |
Mouse Anti Hepatitis C Ns-3 Antigen Monoclonal Antibody |
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DMABT-51341MH | Creative Diagnostics | 0.1 mg | EUR 1513.2 |
Mouse Anti Hepatitis C Ns-4A Antigen Monoclonal Antibody |
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DMABT-51344MH | Creative Diagnostics | 0.1 mg | EUR 1132.8 |
Mouse Anti Hepatitis C Ns-5 Antigen Monoclonal Antibody |
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DMABT-51346MH | Creative Diagnostics | 0.2 mg | EUR 920.4 |
Mouse Anti Hepatitis C Ns-5 Antigen Monoclonal Antibody |
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DMABT-51348MH | Creative Diagnostics | 0.2 mg | EUR 920.4 |
Mouse Anti Hepatitis C Ns-5A Antigen Monoclonal Antibody |
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DMABT-51351MH | Creative Diagnostics | 0.1 mg | EUR 1513.2 |
Mouse Monoclonal Anti-Hepatitis Surface Antigen (HBsAg)-HRP Conjugate |
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HBA12-HRP | Alpha Diagnostics | 1 ml | EUR 416.4 |
Mouse Monoclonal Anti-Hepatitis Surface Antigen (HBsAg) (clone 1) |
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HBA12-M | Alpha Diagnostics | 1 mg | EUR 343.2 |
Mouse Monoclonal Anti-Hepatitis Surface Antigen (HBsAg) (clone 2) |
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HBA13-M | Alpha Diagnostics | 1 mg | EUR 343.2 |
anti-B human blood antigen IgM |
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134-A-01mg | Virogen | 0,1 mg | EUR 321 |
Description: anti-B human blood antigen IgM |
anti-B human blood antigen IgM |
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134-A-1000ug | Virogen | 1000 ug | EUR 1539 |
Description: anti-B human blood antigen IgM |
anti-AB human blood antigen IgM |
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135-A-01mg | Virogen | 0,1 mg | EUR 321 |
Description: anti-AB human blood antigen IgM |
anti-AB human blood antigen IgM |
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135-A-1000ug | Virogen | 1000 ug | EUR 1539 |
Description: anti-AB human blood antigen IgM |
anti-M human blood antigen IgM |
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144-A-01mg | Virogen | 0,1 mg | EUR 321 |
Description: anti-M human blood antigen IgM |
anti-M human blood antigen IgM |
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144-A-1000ug | Virogen | 1000 ug | EUR 1539 |
Description: anti-M human blood antigen IgM |
Blood Antigen ig2b: Anti-N Human |
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145-A-01mg | Virogen | 0,1 mg | EUR 321 |
Description: anti-N human blood antigen Ig2b |
Blood Antigen ig2b: Anti-N Human |
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145-A-1000ug | Virogen | 1000 ug | EUR 1539 |
Description: anti-N human blood antigen Ig2b |
anti-Rabies G antigen monoclonal antibody |
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010-A-01mg | Virogen | 0,1 mg | EUR 321 |
Description: anti-Rabies G antigen monoclonal antibody. Produced against a recombinant protein. |
anti-Rabies G antigen monoclonal antibody |
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010-A-1000ug | Virogen | 1000 ug | EUR 1539 |
Description: anti-Rabies G antigen monoclonal antibody. Produced against a recombinant protein. |
Anti-HBcAG Hepatitis B Core Antigen |
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030-A-01mg | Virogen | 0,1 mg | EUR 321 |
Description: anti-HBcAg core IgM (monoclonal) Produced against recombinant HBcAg core antigen. |
Anti-HBcAG Hepatitis B Core Antigen |
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030-A-1000ug | Virogen | 1000 ug | EUR 1539 |
Description: anti-HBcAg core IgM (monoclonal) Produced against recombinant HBcAg core antigen. |
anti-HBsAg surface antigen IgG1 mAb |
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032-A-01mg | Virogen | 0,1 mg | EUR 321 |
Description: anti-HBsAg surface antigen IgG1 (monoclonal) Produced against HBsAg purified from human sera pool. |
anti-HBsAg surface antigen IgG1 mAb |
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032-A-1000ug | Virogen | 1000 ug | EUR 1539 |
Description: anti-HBsAg surface antigen IgG1 (monoclonal) Produced against HBsAg purified from human sera pool. |
Anti-Retinal S antigen/SAG Antibody |
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A03775 | BosterBio | 100ug/vial | EUR 352.8 |
Anti-Melanoma-associated antigen D1 Antibody |
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A05037 | BosterBio | 100ul | EUR 476.4 |
Description: Rabbit Polyclonal Melanoma-associated antigen D1 Antibody. Validated in WB and tested in Human, Mouse, Rat. |
Anti-TF Antigen Peptide P30-1 |
|||
H-5988.0001 | Bachem | 1.0mg | EUR 283.2 |
Description: Sum Formula: C94H130N26O19; CAS# [573664-50-3] net |
Anti-TF Antigen Peptide P30-1 |
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H-5988.0005 | Bachem | 5.0mg | EUR 1023.6 |
Description: Sum Formula: C94H130N26O19; CAS# [573664-50-3] net |
Anti-Prostate Specific Antigen/KLK3 Antibody |
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PB9259 | BosterBio | 100ug/vial | EUR 352.8 |
Anti-Proximal Nephrogenic Renal Antigen antibody |
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STJ16100515 | St John's Laboratory | 100 µg | EUR 424.8 |
Anti-Endothelial Internalizing Surface Antigen antibody |
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STJ16100681 | St John's Laboratory | 1 mL | EUR 469.2 |
Anti-Carcinoma Associated antigen MAM6 antibody |
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STJ16100874 | St John's Laboratory | 1 mL | EUR 325.2 |
Allium jesdianum hydro alcoholic extract ameliorates diabetic nephropathy by suppressing connective tissue improvement situation (CTGF) and receptor for superior glycation endproducts (RAGE) gene expression in diabetic rats with streptozotocin
Objectives: Diabetic nephropathy is taken into account one among the foremost issues of diabetes, the utilization of medicinal vegetation is rising due to fewer destructive results. This study was designed to take a look at antidiabetic outcomes of Allium jesdianum (A. jesdianum) ethanolic extract and take into account its outcomes on oxidative stress markers and the expression of connective tissue improvement situation (CTGF) and receptor for superior glycation endproducts (RAGE) genes throughout the kidney of kind 1 diabetic rats.
Methods: On this study, we randomly divided 24 rats into four groups with six rats in each group as follows: Cnt group: common administration receiving common saline, Dibt group: diabetic administration receiving common saline day by day, Dibt + A. jesdianum 250 group: diabetic rats receiving A. jesdianum at a dose of 250 mg/kg bw day by day, Dibt + A. jesdianum 500 group: diabetic rats receiving A. jesdianum at a dose of 500 mg/kg bw day by day. To induce diabetes, we used 55 mg/kg bw dose of streptozotocin intraperitoneally. The main focus of fasting blood glucose (FBG) and serum urea, creatinine and albumin, SOD, MDA (using spectrophotometric methods) and gene expression of CTGF and RAGE in kidney tissue (using real-time PCR methods) had been quantified throughout the diabetic rats that obtained A. jesdianum for 42 days, and had been as compared with administration rats.
Outcomes: The outcomes confirmed that in the diabetic group the FBG and serum urea, creatinine and expression of kidney CTGF and RAGE genes and the levels of SOD and MDA significantly elevated and serum albumin significantly decreased as compared with the Cnt group (p<0.001). Administration of A. jesdianum significantly improved the FBG and serum urea, creatinine and albumin as compared with Dibt group (p<0.05). It was confirmed the A. jesdianum significantly decrease the kidney expression ranges of CTGF and RAGE genes and improve oxidative stress (elevated SOD and decreased MDA) throughout the kidney tissues when as compared with Dibt group (p<0.001). Moreover, it was found that the helpful outcomes of the A. jesdianum had been dose-dependent.
Conclusions: The outcomes of this study confirmed that administration of A. jesdianum for 42 days has helpful anti-diabetic and anti-nephropathic ends in diabetic rats and may be utilized as an adjunct treatment throughout the treatment of diabetes.
The interplay of oxidative stress and ARMS2-HTRA1 genetic hazard in neovascular AMD
Age-related macular degeneration (AMD) is the principle purpose for imaginative and prescient loss in adults over 60 years earlier globally. There are two kinds of superior AMD: “dry” and “moist”. Dry AMD is characterised by geographic atrophy of the retinal pigment epithelium and overlying photoreceptors throughout the macular space; whereas moist AMD is characterised by vascular penetrance from the choroid into the retina, typically generally known as choroidal neovascularization (CNV). Every phenotypes lastly end in lack of central imaginative and prescient. The pathogenesis of AMD consists of the interplay of genetic polymorphisms and environmental hazard parts, quite a lot of which elevate retinal oxidative stress.
Further reactive oxygen species react with cellular macromolecules, forming oxidation-modified byproducts that elicit continuous irritation and promote CNV. Furthermore, genome-wide affiliation analysis have acknowledged a variety of genetic variants throughout the age-related maculopathy susceptibility 2/high-temperature requirement A serine peptidase 1 (ARMS2-HTRA1) locus associated to the event of late-stage AMD, significantly the moist subtype. On this consider, we’re going to cope with the interplay of oxidative stress and HTRA1 in drusen deposition, continuous irritation, and continuous angiogenesis. We intention to present a multifactorial model of moist AMD improvement, supporting HTRA1 as a novel therapeutic objective upstream of vascular endothelial improvement situation (VEGF), the usual objective in AMD therapeutics. By inhibiting HTRA1’s proteolytic train, we’re in a position to reduce pro-angiogenic signaling and forestall proteolytic breakdown of the blood-retina barrier. The anti-HTRA1 technique affords a promising completely different treatment option to moist AMD, complementary to anti-VEGF treatment.
Age-related telomere attrition causes aberrant gene expression in sub-telomeric areas
Telomere attrition has been proposed as a biomarker and causal take into consideration rising older. Together with inflicting cellular senescence and apoptosis, telomere shortening has been found to affect gene expression in subtelomeric areas. Proper right here, we analyzed the distribution of age-related differentially expressed genes from the GTEx RNA sequencing database of 54 tissue kinds from 979 human subjects and positioned significantly additional upregulated than downregulated genes in subtelomeric areas as as compared with the genome-wide frequent. Our information present spatial relationships between telomeres and gene expression in rising older.
WEScover: selection between medical whole exome sequencing and gene panel testing
Background: Total exome sequencing (WES) is extensively adopted in medical and evaluation settings; nonetheless, one among many wise points is the potential false negatives due to incomplete breadth and depth of safety for a variety of exons in clinically implicated genes. In some situations, a targeted gene panel testing may be a dependable risk to find out true negatives for genomic variants in acknowledged disease-associated genes. We developed a web-based instrument to shortly gauge whether or not or not all genes of curiosity may very well be reliably coated by WES or whether or not or not targeted gene panel testing must be thought-about as a substitute for cut back false negatives in candidate genes.
Outcomes: WEScover is a novel web utility that offers an intuitive individual interface for finding breadth and depth of safety all through population-scale WES datasets, searching each by phenotype, by targeted gene panel(s) or by gene(s). Moreover, the making use of reveals metrics from the Genome Aggregation Database to current gene-centric view on breadth of safety.
Conclusions: WEScover permits clients to successfully query genes and phenotypes for the safety of associated exons by WES and recommends use of panel exams for the genes with potential incomplete safety by WES.